Listened to the interview with Ludovic Courtès on #LibreLounge. Guix sounds so cool. So many nice features, but one that particularly tickles my fancy at the moment is having the OS config in one file, that you can just rebuild a system with. I was trying to do something like that for Debian a while back, but sounds like Guix has it baked in.

https://librelounge.org/episodes/episode-23-guix-with-ludovic-court%C3%A8s.html